Education
- Ph.D. in Microbiology and Immunology, The Australian National University (ANU)
- M.C.S. in Marketplace, The China Graduate School of Theology (CGST)
- B.Sc. in Biochemistry, First Class Honors, The Chinese University of Hong Kong (CUHK)
Position
- Emeritus Professor, School of Life Sciences, CUHK
- Adjunct Professor, School of Life Sciences, CUHK
- Senior College Tutor, Chung Chi College
- External Examiner, Certificate in Medical Laboratory Science, School of Professional and Continuing Education (SPACE), University of Hong Kong (HKU)
- Academic Assessor, Higher Certificate in Medical Laboratory Science (Biochemistry Module), SPACE, HKU
Research Interests
- Immunopharmacological and biochemical studies on natural products/Chinese medicinal herbs
- Molecular studies on cancer cell proliferation, differentiation and apoptosis
- Nutrition and immunity
Representative Publications
- Liu WM, Leung KN (2015) The immunomodulatory activity of jacaric acid, a conjugated linolenic acid isomer, on murine peritoneal macrophages. PLOS ONE 10:e0143684.
- So WW, Liu WN, Leung KN (2015) Omega-3 polyunsaturated fatty acids trigger cell cycle arrest and induce apoptosis in human neuroblastoma LA-N-1 cells. Nutrients 7:6956-6973.
- Liu WM, Leung KN (2015) Anti-allergic effect of the naturally-occurring conjugated linolenic acid isomer, jacaric acid, on the activated human mast cell line-1. Biomed Rep 3:839-842.
- Liu WM, Leung KN (2015) Jacaric acid inhibits the growth of murine macrophage-like leukemia PU5-1.8 cells by inducing cell cycle arrest and apoptosis. Cancer Cell Int 15:90.
- Liu WM, Leung KN (2014) Apoptosis- and differentiation-inducing activities of jacaric acid, a conjugated linolenic acid isomer, on human eosinophilic leukemia EoL-1 cells. Oncol Rep 32:1881-1888.
- Liao XM, Zhou XL, Mak NK, Leung KN (2013) Tryptanthrin inhibits angiogenesis by targeting the VEGFR2-mediated ERK1/2 signalling pathway. PLOS ONE 8:e82294.
- Liao XM, Leung KN (2013) Indirubin-3’-oxime induces mitochondrial dysfunction and triggers growth inhibition and cell cycle arrest in human neuroblastoma cells. Oncol Rep 29:371-379.
- Liao XM, Leung KN (2013) Tryptanthrin induces growth inhibition and neuronal differentiation in the human neuroblastoma LA-N-1 cells. Chemi-Biol Interact 203:512-521.
- Chan HL, Yip HY, Mak NK, Leung KN (2009) Modulatory effects and action mechanisms of tryptanthrin on murine myeloid leukemia cells. Cell Mol Immunol 6:335-342.
- Cho WCS, Leung KN (2007) In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer Lett 252:43-54.
Awards
- Distinguished Service Award, Hong Kong Society for Immunology (2015)
- Vice-Chancellor’s Exemplary Teaching Award, CUHK (2008)
- Exemplary Teaching Awards, Faculty of Science, CUHK (2008, 2007, 2005, 2004, 2003)
- Award for Outstanding Achievement, International Journal of Molecular Medicine (1998)
- Ph.D. Scholarship, Australian National University (1978 - 81)
Professional Activities
- Member, Hong Kong Society of Flow Cytometry
- Life Member, Hong Kong Society for Immunology
- Member, Hong Kong Society for Biochemistry and Molecular Biology