Mr LIU Man Fai Andrew

Address

(Office): Rm 333B, Science Centre North Block

(Lab): Rm 127, Science Centre North Block

 People LMF
 

Phone

(Office): (852) 3943 1393

(Lab): (852) 3943 1492
Fax (852) 2603 6510
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Web -
 

 

Education

1999 M.Sc., McGill University
1997 B.Sc., McGill University

Position

  • Assistant Lecturer, School of Life Sciences

Research Interests

  • Cell biology
  • Signal transduction of G proteins 

Representative Publications

  • Liu AM, Lo RK, Guo EX, Ho MK, Ye RD, Wong YH. “Ga16 interacts with tetratricopeptide repeat 1 (TPR1) through its b3 region to activate Ras independently of phospholipase Cb signaling” BMC Struct Biol. 2011, 11:17.
  • Liu AM, Lo RK, Lee MM, Wang YC, Yeung WW, Ho MK, Su Y, Ye RD, Wong YH. “Ga16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS) cellular signalling” Cell Signal.2010, 22:1448-58.
  • Liu AM, New DC, Lo KH, Wong YH. "Reporter gene assays", Methods Mol. Biol., 2009, 486:109-23.
  • Liu AM, Lo RK, Wise H, Wong YH. “Activation of the prostacyclin receptor in human erythroleukemia cells leads to STAT3 phosphorylation via Gas and Ga16 hybrid signaling.” Cell Signal., 2008, 20:2095-2106.
  • Liu AM, Kam AK, Wong YH. “FPRL-1 receptor requires lipid raft, Src family tyrosine kinase, PI3K/Akt and ERK to activate IkB kinase in human U87 astrocytoma cells.” J. Neurochem., 2007, 103:1553-1566.
  • Liu AM, Lo RK, Wong CS, Morris C, Wise H, Wong YH. “Activation of STAT3 by Gas distinctively requires PKA, JNK and PI3K”, J. Biol. Chem., 2006, 281:35812-35825.
  • Liu AM, Wong YH. “Activation of nuclear factor kB by somatostatin type 2 receptor in pancreatic acinar AR42J cells involves Ga14 and multiple signaling components: A mechanism requiring PKC, CaMKII, c-Src and ERK.” J. Biol. Chem., 2005, 280:34617-34625.
  • Liu AM, Wong YH. “m-opioid receptor-mediated phosphorylation of IkB kinase in human neuroblastoma SH-SY5Y cells” Neurosignals, 2005,14:136-142.
  • Liu AM, Wong YH. “G16-mediated activation of nuclear factor kB by the adenosine A­1 receptor involves c-Src, protein kinase C, and ERK signaling.” J. Biol. Chem.2004, 279:53196-53204.
  • Liu AM, Somers NA, Kazlauskas RJ et al.. “Mapping the substrate selectivity of new hydrolases using colorimetric screening: lipases from Bacillus thermocatenulatus and Ophiostoma piliferum, esterases from Pseudomonas fluorescens and Streptomyces diastatochromogenes” Tetrahedron: Asymmetry 2001, 12:545-556.