Professor WOO Ying Shiu Norman


(Office): Rm G78, Science Centre South Block

(Lab): LG 105, Run Run Shaw Science Building

People WYS


(Office): (852) 3943 6148

(Lab): (852) 3943 6280

Fax (852) 2603 5646
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
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1976 Ph.D. University of Hong Kong
1973 B.Sc. University of Hong Kong


  • Research Professor, School of Life Sciences

Research Interests

  • Fish osmoregulatory physiology
  • Biology of stress and heat stock proteins
  • Fish diseases

Representative Publications

  • Deane, E. E., Luk, J. C. Y. and Woo, N. Y. S. (2011) Aquaporin 1a expression in gill, intestine and kidney of the euryhaline silver sea bream. Frontiers in Physiology 2: 39 doi: 10.3389/fphys.2011.00039
  • Deane, E. E. and Woo, N. Y. S. (2011) Advances and perspectives on the regulation and expression of piscine heat shock proteins. Reviews in Fish Biology and Fisheries 21: 153-185.
  • Leung, L. Y., and Woo, N. Y. S. (2010) Effects of growth hormone, insulin-like growth factor I, triiodothyronine, thyroxine, and cortisol on gene expression of carbohydrate metabolic enzymes in sea bream hepatocytes. Comparative Biochemistry and Physiology A157: 272-282.
  • Jia, A., Woo, N. Y. S., and Zhang, X.-H. (2010) Expression, purification and characterization of thermolabile hemolysin (TLH) from Vibrio alginolyticus. Diseases of Aquatic Organisms90: 121-127.
  • Bai, F., Sun, B., Woo, N. Y. S., and Zhang, X-H (2010) Vibrio harveyi hemolysin induces ultrastructural changes and apoptosis in flounder (Paralichthys olivaceus) cells. Biochemical and Biophysical Research Communications395: 70-75.
  • Deane, E. E. and Woo, N. Y. S. (2009) Modulation of fish growth hormone levels by salinity, temperature, pollutants and aquaculture related stress: a review. Reviews in Fish Biology and Fisheries 19: 97-120.
  • Kwong, A. K. Y. and Woo, N. Y. S. (2008) Prolactin-releasing peptide, a possible modulator of prolactin in the euryhaline silver sea bream (Sparus sarba): a molecular study. General and Comparative Endocrinology 158: 154-160.
  • Man, A. K. Y. and Woo, N. Y. S. (2008) Upregulation of metallothionein and glucose-6-dehydrogenase expression in silver sea bream, Sparus sarba, exposed to sublethal levels of cadmium. Aquatic Toxicology 89: 214-221.
  • Deane, E. E., Zhou, L. R. and Woo, N. Y. S. (2006) Cortisol can be pro- or anti-apoptotic in sea bream cells: potential role of HSP70 induction for cytoprotection. Molecular and Cellular Endocrinology 259: 57-64.
  • Deane, E. E. and Woo, N. Y. S. (2006) Tissue distribution, effects of salinity acclimation and ontogeny of aquaporin 3 in the marine teleost silver sea bream (Sparus sarba). Marine Biotechnology 8: 663-671.

Research Grants

  • 2011-2013: RGC GRF, Function and regulation of cystic fibrosis transmembrane regulator (CFTR) in gill and intestine of the euryhaline seabream. PI. $690,000
  • 2009-2012: RGC GRF: Do salinity and hormones influence apoptosis and transformation of gill chloride cells? PI, $1,636,666.
  • 2005-2008: RGC Earmarked Grant: Molecular strategies of temperature acclimation in the sea bream. PI, $815,957.
  • 2003-2006: RGC Earmarked Grant: Role of aquaporin water channels in the osmoregulatory strategy of the euryhaline marine teleost Sparus sarba. PI: $1,388,000.
  • 2002-2005: RGC Earmarked Grant: Growth hormone and insulin-like growth factor – I as anti-apoptotic factors via modulated HSP70 expression in sea bream. PI: $1,354,000.
  • 2001-2004 RGC Earmarked Grant: Stimulation of glucose-6-phosphate dehydrogenase activity in sea bream: metabolic significance and potential applications. PI: $1,078,000.
  • 2000-2002 RGC Earmarked Grant: Modulation of gill Na+-K+-ATPase expression by salinity and hormonal factors in the sea bream, Sparus sarba. PI: $679,200.
  • 1999 – 2002 RGC Earmarked Grant: Protective effects of heat shock protein 70 (HSP70) against environmental and pathogenic stress in the marine teleost Sparus sarba. PI: $920,640.
  • 1998-2000 RGC Earmarked Grant: Enhancing immunological competence of silver sea bream (Sparus sarba) through the combined application of salinity adaptation, hormonal factors and specific vaccines. PI: $645,000.
  • 1997-2000: RGC Earmarked Grant: Evaluation of novel microencapsulated formulations for the improved survival and development of cultured marine fish larvae. PI: $849,500.
  • 1995-1997: RGC Earmarked Grant: An iso‑osmotic marine fish factory. PI: $531,000.
  • 1991-1994: RGC Earmarked Grant: An assessment of the feasibility of developing ‘factory‑based' marine fish culture. PI; $400,000.
  • 2004-2009: Area of Excellence (AoE): Centre for Marine Environmental Research and Innovative Technology (MERIT): $925,000.
  • 2009-2012: Area of Excellence (AoE) Extension: Centre for Marine Environmental Research and Innovative Technology (MERIT): $300,000.
  • 2009-2011: NSFC-RGC Joint Research Scheme: Elucidation of the role played by Vibrio virulence factors on cytoprotection and apoptosis in fish cells. PI: $656,400.


  • Ocean Services Award, PACON International, USA
  • Distinguished Member Award, PACON International, USA

Professional Activities

  • Editorial Board, Frontiers in Aquatic Physiology
  • Editorial Board, Journal of Marine Biology
  • Editorial Board, Open Marine Biology Journal


  • Partner Laboratory - State Key Laboratory in Marine Pollution